Centrosome proteins form an insoluble perinuclear matrix during muscle cell differentiation
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چکیده
منابع مشابه
Determination of insoluble avian eggshell matrix proteins.
The organic components of bones and other mineralized tissues have a high impact on the organization and deposition of calcium, and consequently influence the mechanical properties of those tissues. The extractable proteins of avian eggshells have been studied extensively and many of them have been identified; insoluble (non-extractable) proteins have been sparsely studied, however. In the work...
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Harnessing pluripotent stem cells for functional regeneration of various solid tissues, for modeling of disease, or for drug testing and development has been hampered by a poor understanding of the microenvironmental factors that direct stem cell fate. Unlike bone marrow reconstitution with hematopoietic stem cells, which has succeeded for decades in the clinic, implantation of embryonic or ind...
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The protein composition of the insoluble avian eggshell matrix was studied. The determination of these proteins insoluble in water (EDTA-insoluble) was carried out using enzymatic cleavage followed by a high-performance liquid chromatography-mass spectrometry method. The influence of various enzymes on the protein splitting also was studied. The distribution of proteins depends on the type of l...
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Though the essential role of extracellular matrix in biofilm development has been extensively documented, the function of matrix-associated proteins is elusive. Determining the dynamics of matrix-associated proteins would be a useful way to reveal their functions in biofilm development. Therefore, we applied iTRAQ-based quantitative proteomics to evaluate matrix-associated proteins isolated fro...
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Membrane proteins play crucial roles in cellular processes and are often important pharmacological drug targets. The hydrophobic properties of these proteins make full structural and functional characterization challenging because of the need to use detergents or other solubilizing agents when extracting them from their native lipid membranes. To aid membrane protein research, new methodologies...
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ژورنال
عنوان ژورنال: BMC Cell Biology
سال: 2009
ISSN: 1471-2121
DOI: 10.1186/1471-2121-10-28